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- $Unique_ID{BRK00577}
- $Pretitle{}
- $Title{Lazy White Blood Cells}
- $Subject{immune leukocytes white blood cell cells Ill Defined Symptoms symptom
- mouth tongue gum gums stomatitis gingivitis Lazy Leukocyte Syndrome Inhibitory
- Factor LIF neutrophils neutrophil}
- $Volume{U-7, N-11}
- $Log{
- Lymphocyte (White) Blood Cells*0002105.scf}
-
- Copyright (c) 1991-92,1993 Tribune Media Services, Inc.
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- Lazy White Blood Cells
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- QUESTION: I have suffered since childhood with repeated infections of my gums
- and tongue. Although I have had excellent dental care, the condition keeps
- coming back. I recently visited a hematologist who felt that my problem could
- be related to "lazy white blood cells", and that the condition was not
- serious, just something to live with. Can you amplify on that explanation?
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- ANSWER: Only with some difficulty, as you have not provided me too much to
- work with. I have focused in on the word "lazy" and discovered an antiquated
- syndrome called the "Lazy Leukocyte Syndrome". First described in 1971 in an
- article by Dr. M.E. Miller published in the British medical journal LANCET, it
- described white blood cells, "leukocytes", that failed to function in normal
- fashion. Rather than attacking foreign poisons in the system, they moved
- about in random fashion, and did not respond to the stimulus of the chemicals
- that could present a threat to the body. As a result, patients suffered from
- recurring infections of mouth and gums (stomatitis and gingivitis). Both men
- and women seemed affected in about equal numbers and the condition often
- started in early childhood. No treatment is noted. Of late we have
- discovered the presence of a substance, "Leukocyte Inhibitory Factor" (LIF),
- which may be the chemical which causes the neutrophils to desert their
- responsibilities in defending our bodies against toxic invaders. A physician
- who specializes in Immunology might be able to afford you additional
- explanations, if you do, in fact, have this unusual syndrome.
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- The material contained here is "FOR INFORMATION ONLY" and should not replace
- the counsel and advice of your personal physician. Promptly consulting your
- doctor is the best path to a quick and successful resolution of any medical
- problem.
-